Ganglioneuromas

Ganglioneuromas are rare, benign tumors that develop from nerve cells called ganglion cells and nerve fibers. These tumors are typically slow-growing and noncancerous.

Ganglioneuromas can arise from various locations within the autonomic nervous system, including the adrenal gland, chest, abdomen, pelvis, and neck.

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Common characteristics of ganglioneuromas include a mixture of mature nerve cells, supportive tissue, and abnormal nerve cells. These tumours are often well-defined and encapsulated, and they do not typically invade surrounding tissues or metastasize to other parts of the body.

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Ganglioneuromas may not cause symptoms in many cases, especially if they are small and not pressing on nearby structures. However, depending on their location and size, they may lead to symptoms such as pain, compression of nearby organs, or hormonal imbalances if they affect the adrenal glands.

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Treatment for ganglioneuromas often involves surgical removal of the tumour, especially if it is causing symptoms or complications. In cases where complete removal is not possible or if the tumour is asymptomatic, close monitoring with regular imaging studies may be recommended.